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Massimiliano Allegri is back in charge of Juventus after two years away
With Serie A getting underway six weeks after Italy's triumph at Euro 2020, the 2021/22 season is in full swing across Europe.
AFP Sport previews the pick of the action on the continent, as Lionel Messi waits for his Paris Saint-Germain debut, his old club focus on life after the Argentine, and Inter Milan begin their defence of the Scudetto.
Brest v Paris Saint-Germain, Friday 1900 GMT
While PSG wait for Lionel Messi to make his debut, along with Sergio Ramos and Gianluigi Donnarumma, they have been busy trying to quash speculation about the future of Kylian Mbappe. Will he leave for Real Madrid? Or will he extend his contract which expires after this season?
In the meantime Mbappe has done his talking on the field -- while Messi and Neymar are yet to feature this season, the France striker set up four goals in PSG's first two matches, wins over Troyes and Strasbourg.
On Friday Mauricio Pochettino's Parisians take on Brest, a club who have not beaten PSG since 1985 and whose entire operating budget would not cover Messi's annual salary.
Inter Milan v Genoa, Saturday 1630 GMT
For fans of Inter, the joy at seeing their team win last season's Serie A title -- and thereby end the long period of Juventus domination in Italy -- has evaporated over a summer in which they have lost their coach, Antonio Conte, and their top scorer Romelu Lukaku.
Cost cutting from Chinese owners Suning saw Conte leave with Simone Inzaghi coming in from Lazio to replace him. Lukaku has been sold to Chelsea while star right-back Achraf Hakimi left for PSG.
It's not entirely doom and gloom though, as Edin Dzeko and Denzel Dumfries arrived as replacements and Turkey's Hakan Calhanoglu joined from rivals AC Milan.
Inter face Genoa at San Siro in their opening game and fans will be back -- the Italian government has permitted clubs to open stadiums to 50 percent capacity.
Athletic Bilbao v Barcelona, Saturday 2000 GMT
For Barcelona, the first game of the post-Messi era could hardly have gone better as Ronald Koeman's side beat Real Sociedad 4-2. Now they go away to face more Basque opposition with a visit to Athletic Bilbao.
The opening game was a reminder that Barca still have a strong starting XI, from Gerard Pique and Jordi Alba at the back, to Sergio Busquets, Frenkie de Jong and Pedri in midfield and Memphis Depay and Antoine Griezmann up front.
Pique scored against Real Sociedad but could miss out with a calf problem against Athletic. Barca won 3-2 the last time these sides met in Bilbao, with Messi scoring twice.
Bayern Munich v Cologne, Sunday 1530 GMT
Julian Nagelsmann already has his first trophy since becoming Bayern Munich coach after his new side beat Borussia Dortmund 3-1 to win the German Super Cup on Tuesday. Now he makes his home debut as the Bundesliga champions face Cologne at the Allianz Arena.
Bayern are looking for their first win of the league campaign in what will also be their first home game since the death of legendary goal-scorer Gerd Mueller last weekend.
Cologne only escaped relegation last season after beating second-tier side Holstein Kiel in a two-legged play-off. It is 10 years since they defeated Bayern but they do head to the Allianz Arena fresh from beating Hertha Berlin on opening day.
Udinese v Juventus, Sunday 1630 GMT
An old face has returned to begin a new era at Juventus. After Inter ended their run of nine successive titles, Juve got rid of coach Andrea Pirlo and re-appointed Massimiliano Allegri.
Winner of five titles in five seasons before departing in 2019, Allegri begins his second spell away at Udinese. Eyes will be on the returning coach but also on Cristiano Ronaldo, who at 36 was the top scorer in Serie A last season.
This week he rubbished reports he was seeking a move away from Juve to return to Real Madrid.
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