Victor Osimhen's opener against Cagliari was his fourth Serie A goal this season
Napoli maintained their perfect start to the Serie A season on Sunday with a 2-0 win over Cagliari which ensured they reclaimed top spot, while Lazio won an eventful derby 3-2 to down Jose Mourinho's Roma.
Luciano Spalletti's side cruised to their sixth victory in as many league games against a Cagliari team coached by former Napoli manager Walter Mazzarri thanks to Victor Osimhen's sixth goal in all competitions this month and a second-half penalty from Lorenzo Insigne who pre-match celebrated his 400th Napoli appearance.
They are two points ahead of AC Milan after another confident display that ends a week in which they scored 10 goals without reply in three league matches.
"The best way to celebrate was to win and score a goal," said Insigne to DAZN, who is four goals away from Diego Maradona's Napoli total of 115.
"We did it together as a team. We've got to keep our feet on the ground, keep our heads down and work because there is a very, very long way to go."
Next weekend Napoli travel to Fiorentina in what will be the first true test of their title credentials, as their 2-1 win over Juventus earlier this month came against a team missing a host of starters.
They made easy work of a passive Cagliari, with Osimhen making it four Serie A goals in five appearances this campaign in the 11th minute when he met Piotr Zielinski's low cross with a typically assured finish.
Osimhen was involved again when a low-key match was settled in the 57th minute, the in-form Nigeria attacker being cleaned out by Diego Godin and Insigne lashing home the subsequent penalty to ensure a simple win.
Goals from Sergej Milinkovic-Savic, Pedro and Felipe Anderson gave Lazio a tight derby win over Roma at a raucous Stadio Olimpico which saw two teams attack each other for 90 minutes.
Maurizio Sarri's side were winless in three league matches heading into the weekend but now sit sixth on 11 points, seven behind Napoli and just one behind fourth-placed Roma, who twice pulled goals back through Roger Ibanez and Jordan Veretout.
In the aftermath Mourinho lashed out at referee Marco Guida and the VAR officials after what he saw as a clear foul on Nicolo Zaniolo just before Lazio launched the counter-attack which ended with former Roma player Pedro putting Lazio 2-0 ahead in the 19th minute.
"The referee and VAR weren't up to the standards of a match of this level. From 2-0 it could have been 1-1, the referee made a mistake on the field and VAR made a mistake... they all made a mistake," Mourinho said to DAZN.
Juventus will have to face Chelsea in the Champions League without Paulo Dybala after the Argentina forward limped off with a thigh injury early in their 3-2 win over Sampdoria.
Dybala opened the scoring with nine minutes on the clock at a wet Allianz Stadium, with Leonardo Bonucci and Manuel Locatelli netting the other goals to move Juve ninth on eight points, but soon afterwards the 27-year-old left the field in tears after the latest in a long line of injuries.
Massimiliano Allegri's side host European champions Chelsea on Wednesday and the coach said Dybala and centre-forward Alvaro Morata, who also exited with a thigh problem towards the end of the match, would be out of action until after the next international break which runs from after next weekend's matches to October 15.
Fiorentina bounced back from midweek defeat to Inter Milan with a battling 1-0 win at Udinese which moved them into fifth on 12 points, six behind Napoli.
Promoted Empoli are threatening the European places after beating Bologna 4-2 to win their second match on the bounce and climb up to eighth, while Salernitana remain rooted to the bottom of the league with a single point after losing 1-0 at Sassuolo.